Closed Lipped Schizencephaly
Findings:
A closely apposed, gray matter lined cleft extends to
the left lateral ventricle from the left frontal cortex. Septum pellucidum
is absent.
Differential Diagnosis:
closed lipped schizencephaly, gray matter heterotopia,
hamartoma.
Discussion:
-most commonly migrational anomaly occurring at
approximately 6 weeks gestation.
-other migrational anomalies: lissencephaly, polymicrogyria,
pachygyria
-infarct vs. developmental, TORCH
-50% have septo-optic dysplasia
-80% rule- bilateral, open, symmetric