Mesial Temporal Sclerosis

Findings:
Coronal T2 weighted images show abnormal increased signal in the hippocampus bilaterally, associated with white matter thinning in these areas and decreased volume of the hippocampal formations. The changes are slightly more pronounced on the right.

Discussion:
In the workup of chronic seizure disorder, attention is focused to the medial temporal lobes. Mesial temporal sclerosis is the most common process found, but other lesions seen include ganglioglioma, cavernoma, dysembryoplastic neuroepithelial tumor, and astrocytoma. Diagnostic criteria of MTS include volume loss and increased signal in the affected temporal lobe. The process may be bilateral asymmetric or unilateral.

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