Inverting Papilloma

Findings:
Coronal and axial CT of the sinuses shows a large expansile mass involving the right maxillary sinus with extension into the nasal cavity and ethmoids.

Differential Diagnosis:
The appearance is somewhat nonspecific. Since the lesion expands and remodels bone rather than destroys it, malignancies such as squamous cell carcinoma, esthesioneuroblastoma, and salivary gland tumors would be relatively unlikely. Reasonable possibilities include inverting papilloma, antrochoanal polyp, or mucocele.

Discussion:
Inverting papillomas are most common in middle aged males and present with unilateral nasal obstruction. The tumors are histologically benign, but foci of squamous cell carcinoma within the lesion are not uncommon. The tumors usually arise from the lateral nasal wall and extend into the maxillary and ethmoid sinuses. Bone destruction may be seen and is usually the result of pressure necrosis rather than tumor permeation. The lesions enhance homogenously, and may have intermediate/low signal on T2WI. The maxillary sinus infundibulum is typically markedly widened. The etiology of the lesions is unknown.

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