Fibrous Dysplasia

nPathology: normal bone marrow replaced by fibrovascular tissue and variable ossification
nDiffuse or monostotic. 20% craniofacial
nCT
nVariable, ground glass, lytic, sclerotic
nSmooth bone remodeling
nMR
nLow signal on all sequences, variable T2 hyperintensities
nVariable enhancement, possibly intense
nComplications:
nSinus obliteration, orbital/facial deformity, skull base foramina

nRare malignant transformation- 0.5%

 

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