Olivopontocerebellar Degeneration

Findings:
severe atrophy of cerebellum and pons

Differential Diagnosis:
OPC degeneration, EtOH abuse, AIDS (OPC only one that would be limited to CB and pons), Shy-Drager syndrome

Discussion:
clinical sx- ataxia, Parkinson-like symptoms
primary degeneration centers in pontine nuclei, associated with pontine, cerebellar, brachium pontis atrophy. helpful sign: PD increased signal in transverse pontine fibers
hereditary vs. sporadic

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